When acute pancreatitis needs surgery
Surgery is reserved for infected pancreatic necrosis (typically >4 weeks after onset, when collections are walled-off) or sterile necrosis with persistent organ failure. Modern management follows a step-up approach: percutaneous drainage first, then minimally-invasive video-assisted retroperitoneal debridement (VARD), then open necrosectomy only if needed. This approach has halved mortality compared to early open surgery.

